The tropics, helminth infections and hygiene hypotheses
نویسندگان
چکیده
منابع مشابه
The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections
Current iterations of the hygiene hypothesis suggest an adaptive role for helminth parasites in shaping the proper maturation of the immune system. However, aspects of this hypothesis are based on assumptions that may not fully account for realities about human helminth infections. Such realities include evidence of causal associations between helminth infections and asthma or inflammatory bowe...
متن کاملChildhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses
The hygiene hypothesis states that childhood asthma develops as a result of decreased exposure to infectious agents during infancy and early childhood. This results in the persistence of the neonatal T helper lymphocyte 2 immunophenotype, thereby predisposing the child to atopic disease. While multiple studies support the hygiene hypothesis in asthma ontogeny, the evidence remains inconclusive;...
متن کاملPregnancy and helminth infections
It has been proposed that helminth infection may be particularly detrimental during pregnancy, through adverse effects on maternal anaemia and on birth outcomes, and that anthelminthic treatment during pregnancy will therefore be particularly beneficial. However, the few treatment trials that have been conducted have given, but little support to this notion and further trials in settings of nut...
متن کاملMalnutrition and parasitic helminth infections.
The Global Burden of Disease caused by the 3 major intestinal nematodes is an estimated 22.1 million disability-adjusted life-years (DALYs) lost for hookworm, 10.5 million for Ascaris lumbricoides, 6.4 million for Trichuris trichiura, and 39.0 million for the three infections combined (as compared with malaria at 35.7 million) (World Bank, 1993; Chan et al. 1994); these figures illustrate why s...
متن کاملMaternal helminth infections.
© Springer Science+Business Media New York 2014 W. Horsnell (ed.), How Helminths Alter Immunity to Infection, Advances in Experimental Medicine and Biology 828, DOI 10.1007/978-1-4939-1489-0_2 C. Prazeres da Costa () · K. Straubinger Department of Parasitology, Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, Trogerstrasse 30, 81675 Munich, Germany e-m...
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ژورنال
عنوان ژورنال: Expert Review of Clinical Immunology
سال: 2018
ISSN: 1744-666X,1744-8409
DOI: 10.1080/1744666x.2018.1424543